The series follows curious, adventure-loving, mischief-making, proudly nerdy, 12-year-old Ace Ripley who suddenly learns he holds an incredible ability to manipulate DNA by fusing the genes of a living thing with any other thing, to create something entirely new. The hero-in-the-making uses his newfound power to create ridiculous, amazing, and even terrifying mashed up creatures, and tries to save his town from total chaos while trying to have the time of his life.