The show follows the titular 21-year-old Lucy, who lives in San Francisco and has been tapped by her father, the devil, to fulfill her destiny as the Antichrist, whether she likes it or not. Along the way she meets up with a DJ — Jesús — who turns out to be the second coming of the messiah and the two begin dating from the first episode after Lucy saves him from a fire created by her father to kill him.
